Psoriasis is a chronic; T lymphocyte mediated autoimmune inflammatory disorder characterized by red patches covered by silvery white scales. These patches may itch and be quite uncomfortable as well as be a cosmetic embarrassment. More than 5.5 million people are affected by this disease in United States. Psoriasis rarely life threatening, It is related with significant healthcare costs, economic losses, and quality of life. The main parts of body involved are the elbows, knees, gluteal cleft and the scalp. There are mainly five types of psoriasis such as plaque psoriasis, guttate psoriasis, pustular psoriasis, inverse psoriasis, erythrodermic psoriasis. Nearly, 80% of patients suffering from psoriasis have plaque psoriasis. Treatment of psoriasis depends on the type and severity of the psoriasis. Mild forms of psoriasis can be adequately treated with over-the-counter or topical preparations. Patients with more severe forms of psoriasis, such as psoriatic arthritis, require intensive therapy with systemic drugs. In this article, we review various approaches for treatment of psoriasis. This review also includes various novel drug delivery system used o treat psoriasis.
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